repair of potentially lethal damage

In this paper a close relationship among the activity of ADP-ribose transf-erase ( ADPRT), rejoining of DNA single strand breaks ( SSB) and potentially lethal damage repair ( PLDR) in mouse tumor cells has been demonstrated.

本文探讨了ADP&核糖基转移酶（ADPRT）的活性、DNA单链断裂（SSB）重接和细胞潜在致死质损伤修复（PLDR）三者的关系。

However, wether repairing of damaged telomeres is a mechanism of potentially lethal damage repair has not been clarified until now, and little is understood about the mechanism of telomerase performing repairing at damaged telomeres and modifying apoptosis.

目前对端粒损伤修复是否是潜在致死性损伤修复中重要的机制还未见有学者明确提出，对端粒酶如何参与端粒损伤的修复及凋亡的调控机制了解还很少。